Antibiotic resistance rates and illnesses caused by antibiotic-resistant organisms are on the rise.Antimicrobial overuse and misuse, as well as the need to optimize antimicrobial usage, are keycontributors to resistance development. Although bacterial coinfection rates were modest incoronavirus illness, antibiotic consumption rates were relatively high. 2019 Antibiotic stewardshipprograms (ASPs) attempt to improve patient outcomes, reduce hospital costs, and avoid antibioticresistance by optimizing antimicrobial prescribing patterns. Clinicians may be directed to administerantibiotics based on the presentation of patients with severe coronavirus illness in 2019. Becauseprimary evidence implies that bacterial infection is uncommon in COVID 19, antibiotic selection throughCOVID 19 may promote antibiotic resistance. As a result, it's critical to keep antimicrobial stewardshipinitiatives going. The widespread use of antibiotics in the ICU has significant ecological consequences,promoting the spread of multidrug-resistant bacteria (MDRB) in this setting. As a result, the main goalsof AMS programs in the ICU are to improve infection control and reduce AMR during the pandemic.Antibiotic resistance rates and illnesses caused by antibiotic-resistant organisms are on the rise.Antimicrobial overuse and misuse, as well as the need to optimize antimicrobial usage, are keycontributors to resistance development. The number of people who used antibiotics was extremelysignificant.