This article examines the otherness of Jews and Muslims after their conversion to Christianity in TheMerchant of Venice and Othello: The Moor of Venice. The article argues that Shakespeare criticizes Venice, asits inhabitants appear to accept the converts and their residence in the city for the purpose of benefiting Veniceeconomically and politically. Specifically, the article investigates how Jews (Shylock and Jessica in TheMerchant) and Muslims (Othello in Othello) are ostracized and mistreated regardless of whether the conversionis willing or forced. In order to investigate this prejudice, the article considers the views of historians of andtravelers to Venice about discrimination in the city during the Renaissance. It also refers to social critics‟ views(such as Fredrick Russell‟s) about the Christians‟ suspicion of the efficacy of the converts‟ baptisms. Thearticle concludes that Shakespeare manifests that Venice is not a mythical city as it is imagined in the Englishand European mind; rather, Venice alienates and humiliates its non-Christian Venetian subjects.Keywords: conversion to Christianity, Merchant of Venice, Othello, otherness, Venice