Moamar Al-Jefout M.D, Kirsten Black M.D.a, b, Lauren Schulke M.Sc.a, b, Marina Berbic B.Med.Sc.a, Georgina Luscombe Ph.D.a, Natsuko Tokushige Ph.D.a, Frank Manconi Ph.D.a, Robert Markham Ph.D.a, Ian S. Fraser M.D.a, b
| a | Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia |
| b | Royal Prince Alfred Hospital, Missenden Road, Camperdown, Australia |
| c |
Muta'h Medical Faculty, Muta'h University, Jordan |
Volume 92, Issue 3, September 2009, Pages 1104-1106
Received 26 September 2008; revised 6 January 2009; Accepted 3 February 2009. Available online 27 March 2009.
Abstract
Endometrial polyps are benign lesions frequently identified in women with infertility or abnormal uterine bleeding in the reproductive and postmenopausal phases We report the striking observation that the numbers of activated mast cells expressing tryptase are increased more than sevenfold throughout the cycle in endometrial polyps (n = 20) compared with normal endometrium. This novel finding has important implications for growth, development, and symptoms associated with polyps in many different tissues.
