Research Priorities for Endometriosis: Recommendations From a Global Consortium of Investigators in Endometriosis

Reproductive Sciences June 30, 2016 ******9116654991.

 

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  1. Peter A. W. Rogers, BSc, PhD1
  2. G. David Adamson, MD2,3
  3. Moamar Al-Jefout, MD, PhD4
  4. Christian M. Becker, MD5
  5. Thomas M. D’Hooghe, MD, PhD6
  6. Gerard A. J. Dunselman, MD, PhD7
  7. Asgerally Fazleabas, PhD8
  8. Linda C. Giudice, MD, PhD3,9,10
  9. Andrew W. Horne, MBChB, PhD11
  10. M. Louise Hull, BSc, MBChB, PhD12
  11. Lone Hummelshoj3,10
  12. Stacey A. Missmer, ScD3,13
  13. Grant W. Montgomery, PhD14
  14. Pamela Stratton, MD15
  15. Robert N. Taylor, MD, PhD10,16
  16. Luk Rombauts, MD, PhD3,10,17
  17. Philippa T. Saunders, PhD18
  18. Katy Vincent, MRCOG, DPhil5
  19. Krina T. Zondervan, DPhil5,19 for the WES/WERF Consortium for Research Priorities in Endometriosis

 

Abstract

The 3rd International Consensus Workshop on Research Priorities in Endometriosis was held in São Paulo on May 4, 2014, following the 12th World Congress on Endometriosis. The workshop was attended by 60 participants from 19 countries and was divided into 5 main sessions covering pathogenesis/pathophysiology, symptoms, diagnosis/classification/prognosis, disease/symptom management, and research policy. This research priorities consensus statement builds on earlier efforts to develop research directions for endometriosis. Of the 56 research recommendations from the 2011 meeting in Montpellier, a total of 41 remained unchanged, 13 were updated, and 2 were deemed to be completed. Fifty-three new research recommendations were made at the 2014 meeting in Sao Paulo, which in addition to the 13 updated recommendations resulted in a total of 66 new recommendations for research. The research recommendations published herein, as well as those from the 2 previous papers from international consensus workshops, are an attempt to promote high-quality research in endometriosis by identifying and agreeing on key issues that require investigation. New areas included in the 2014 recommendations include infertility, patient stratification, and research in emerging nations, in addition to an increased focus on translational research. A revised and updated set of research priorities that builds on this document will be developed at the 13th World Congress on Endometriosis to be held on May 17–20, 2017, in Vancouver, British Columbia, Canada.